T activation haemolysis and death after blood transfusion.
نویسندگان
چکیده
A 30 week gestation infant developed necrotising enterocolitis associated with Clostridium perfringens septicaemia at 3 weeks of age. He responded to treatment with intravenous fluids, antibiotics, and blood, but his blood haemolysed. Because of anaemia further blood was given, but, within minutes he died. Examination of his red cells showed an increase in T activation.
منابع مشابه
A Root Cause Analysis of Haemolysis Encountered in Leuco-filtration of Stored Packed Red Cells Units
Background and Aims: Leukoreduction of blood components has reduced the incidence of transfusion-associated adverse events. Leucofiltration is the most effective method of leukoreduction. We encountered haemolysis in a series of leucofiltered units. This stressed our precious inventory, added to financial loss, increased our turn-around time to issue leucofiltered blood units, and placed doubts...
متن کاملBlood transfusion in premature or young infants with polyagglutination and activation of the T antigen.
It is known from the literature that severe haemolytic transfusion reactions may occur in premature infants or young children with an activated T antigen when they are transfused with blood or plasma-containing blood components from donors with strong anti-T. It has come to our attention that in some transfusion centres, the provision of blood or blood components for such infants or children is...
متن کاملAcute naphthalene poisoning following the non-accidental ingestion of mothballs.
Ingestional naphthalene mothball poisoning leading to prolonged haemolysis and methaemoglobinaemia can present with diagnostic and therapeutic challenges. A 19-year-old woman ingested 12 mothballs, and presented two days later with haemolysis and methaemoglobinaemia. She was treated with red blood cell transfusions, intravenous methylene blue, N-acetylcysteine and ascorbic acid. Continuous veno...
متن کاملDelayed haemolysis after artesunate therapy in a cohort of patients with severe imported malaria due to Plasmodium falciparum.
INTRODUCTION Delayed haemolytic anaemia is one of the more frequent events after treatment with intravenous artesunate in patients with severe malaria. Little is known about its frequency and the outcomes of patients with this condition. METHODS A retrospective study was conducted to describe the incidence of delayed haemolysis in a cohort of patients with severe malaria by Plasmodium falcipa...
متن کاملMassive acute haemolysis in neonates with glucose-6-phosphate dehydrogenase deficiency.
Three neonates with glucose-6-phosphate dehydrogenase (G6PD) deficiency are described. All three patients suffered an episode of massive acute haemolysis, in the absence of blood group incompatibilities, infection, or ingestion of oxidising agents known to trigger haemolysis. One patient died, but the other two survived after an exchange transfusion. This highlights that G6PD deficiency in the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Archives of disease in childhood
دوره 62 7 شماره
صفحات -
تاریخ انتشار 1987